WebNov 6, 2024 · Eligible patients were randomized in a 1:1 fashion to either empagliflozin 10 mg daily (n = 3,304) or placebo (n = 3,305). Total screened: 8,544. Total number of enrollees: 6,609. Duration of follow-up: 2 years. Mean patient age: 64 years. Percentage female: 33%. Inclusion criteria: Age ≥18 years or at “full age” as required by local ... WebNov 1, 2024 · A. SGLT2 inhibitors safely reduce the risk of kidney disease progression, acute kidney injury, cardiovascular death, and hospitalization for heart failure (HF) in patients with chronic kidney disease (CKD) or HF, irrespective of diabetes status, according to results from the EMPA-KIDNEY meta-analysis presented Nov. 6 during AHA 2024 and ...
Will Herrington — Nuffield Department of Population Health
WebMar 16, 2024 · With the Population Health Research Unit at University of Oxford conducting the phase 3 trial, the primary endpoint was a composite of kidney disease progression, which included the initiation of maintenance dialysis or receipt of a kidney transplant, a sustained decline in eGFR to below 10 mL/min/1.73 m2, renal death or a sustained … WebHe is Chief Investigator of the EMPA-KIDNEY trial which tested the effects of empagliflozin 10mg versus placebo on cardiorenal outcomes in 6609 people with chronic kidney … eku public relations
Rationale and protocol of the Dapagliflozin And ... - Oxford …
WebNov 22, 2024 · The Oxford University-based research team that ran EMPA-Kidney immediately plugged the results into a meta-analysis that included 12 additional trials involving an SGLT2 inhibitor in more than ... WebJun 23, 2024 · Conclusions: EMPA-KIDNEY will evaluate the efficacy and safety of empagliflozin in a widely generalizable population of people with CKD at risk of kidney … WebJul 20, 2024 · Study Description. The primary aim of the study is to investigate the effect of empagliflozin on kidney disease progression or cardiovascular death versus placebo on … foodboom italy