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WebSeveral classes of zinc-finger motifs are present in transcription factors and function as parts of DNA-binding and protein-protein interaction domains. Most of the known … WebIn molecular genetics, the Krüppel-like family of transcription factors ( KLFs) are a set of eukaryotic C2H2 zinc finger DNA-binding proteins that regulate gene expression. This family has been expanded to also include the Sp transcription factor and related proteins, forming the Sp/KLF family. [1] Members [ edit] diamond shaped headphones

UniProt

WebSymbol Description Category UniProt ID GIFtS GC id Score; 2701: SIAH3: Siah E3 Ubiquitin Protein Ligase Family Member 3: Protein Coding: Q8IW03: 37: GC13M045777: 0.34 WebDNL-type zinc finger: RGD ID: 1308635: Description: Predicted to enable chaperone binding activity. Predicted to be involved in protein folding; protein import into mitochondrial matrix; and protein stabilization. ... Type: protein-coding RefSeq Status: VALIDATED: Previously known as: LOC296587; MGC189536; RGD1308635; similar to CG12379-PA ... Zinc finger (Znf) domains are relatively small protein motifs that contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not, instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), howe… cisco router bufferbloat