WebAdipo- is a combining form used like a prefix meaning “fat, fatty tissue.” It is often used in medical and scientific terms, including in biology and chemistry. Adipo- ultimately comes … WebOur data demonstrate that Cxcl12-abundant-reticular (CAR) cell subsets (Adipo-CAR and Osteo-CAR) differentially localize to sinusoidal and arteriolar surfaces, act locally as …

Vascular Regulation of Hematopoietic Stem Cell Homeostasis

WebMar 2, 2024 · The quiescent pre-adipocyte-like subset of CXCL12 + stromal cells ("Adipo-CAR" cells) is localized to sinusoidal surfaces and particularly enriched for hematopoiesis-supporting cytokines. However, detailed characteristics of these CXCL12 + pre-adipocyte-like stromal cells and how they contribute to marrow adipogenesis remain largely unknown. WebAug 11, 2024 · Expression of adiponectin also defines the major BMAd progenitor, termed ‘Adipo-CAR’ cells (adipogenic CXCL12-abundant reticular) or ‘MALP’ (marrow adipogenic lineage precursor) ( Zhong et al., 2024; Matsushita et al., 2024; Baccin et al., 2024 ). inlet hose washing machine

The Essential Functions of Adipo-osteogenic Progenitors as ... - Immunity

WebOsteo-CAR and Adipo-CAR cells (11), instead of a uniform entity as adipo-osteogenic progenitors (Figure 1). Osteo-CAR cells express both Cxcl12 and Alpl (encoding alkaline The frequencies of the various BM cell types differ by several orders of magnitude11, imposing a challenge to scRNAseq approaches. To capture both highly abundant and extremely rare BM-resident cells, we performed droplet-based scRNAseq12 of cells from total mouse BM, followed by progressive depletion of the … See more To confirm the spatial relationships of BM cell types identified by LCM-seq, we determined marker combinations specific to the individual … See more Key biological processes occurring in the BM are thought to be mediated by the coordinated action of a diverse set of cytokines and growth … See more We applied RNA-Magnet to soluble signalling mediators (for example cytokines, growth factors and so on) and their receptors to … See more WebThe quiescent pre-adipocyte-like subset of CXCL12+stromal cells (“Adipo-CAR” cells) is localized to sinusoidal surfaces and particularly enriched for hematopoiesis-supporting cytokines. However, detailed characteristics of these CXCL12+pre- adipocyte-like stromal cells and how they contribute to marrow adipogenesis remain largely unknown. inlet hose miele dishwasher